Hormone replacement therapy involves restoring estrogen (female hormone) to your body when your levels are diminished. Menopause is the most common cause of low estrogen levels. During menopause your ovaries (glands that produces eggs and hormones) stop producing estrogen and you no longer menstruate.

Women who have had their ovaries surgically removed have decreased levels of estrogen and experience the same symptoms and physical changes associated with menopause.



If a woman has an intact uterus, unopposed estrogens are associated with endometrial hyperplasia and carcinoma. Therefore, almost all such women should also be given a progestin. In women who have had a hysterectomy, progestins need not be added, and unopposed estrogens are most commonly used.

4 Corners Pharmacy are able to supply the following Estrogens.

Estradot / Vivelle – Estrogen Patch.

Climara – Estrogen Patch.

Estraderm – Estrogen Replacement Patch.

Estrofem – Estrogen Replacement.

Premarin – Conjugated Equine Oestrogen.

Ethinyl Estradiol
Ethinylestradiol (Synthetic Estrogen) is most frequently used as the estrogen component of combined oral contraceptives.

Progynova – Progynova is equivalent to natural 17-β-estradiol which is found in Estrace. Estrace contains micronized 17-β-estradiol.

Progynova TS – is a transdermal patch. Progynova patches are oval transparent patches with a self-adhesive backing which can be stuck to the skin. Progynova is equivalent to natural 17-β-estradiol which is found in Estrace.

Sandrena – Estrogen Gel

Aerodiol nasal spray – nasal spray containing estradiol hemihydrate.

Vagifem – Estradiol Vaginal tablet.

Premarin Cream – Vaginal estrogens reverse postmenopausal atrophy of the vaginal lining, thickening the lining and increasing its secretions.

Ovestin – Ovestin contains the natural hormone estriol, which is a weak estrogen. It treats urogenital symptoms without causing adverse changes to the endometrium, which means that it can be used without a progestogen in women with an intact uterus.

Ovestin Cream – This cream contains the hormone Estriol which is a naturally occurring oestrogen. Ovestin is used by post-menopausal women to relieve local symptoms of the vulva & vagina such as dryness and inflammation of the skin layer.

Estrodose is the same medication as Estrogel
It is a clear, non-greasy, non-staining, odourless transdermal gel containing the female hormone oestrogen (0.06% w/w 17β oestradiol).


Estrogen, alone, may increase a women’s risk of endometrial cancer. Because of this, most Health care providers will advise that you take progesterone with estrogen — progesterone prevents endometrial cancer. Women who have had their uterus removed (hysterectomy) need not worry about endometrial cancer.

4 Corners Pharmacy is able to supply the following Progesterones.


Provera also known as Cycrin.

Depo-Provera – has synthetic progesterone and no estrogen.

Crinone (Also sold under the brand name Procheive) – Progesterone Gel .4% and .8%.
Crinone which is also sold under the brand name Proceheive is a natural form of progesterone, the vaginal gel has one major benefit: Because it is applied through your vagina and goes to your uterus, the progesterone is absorbed right where you need it most.
Crinone (Prochieve) currently the only natural progesterone bio-adhesive gel on the market, was introduced in 1998. It comes in two different formulations — 8%, which is used for infertility treatments, and 4% which is used for HRT.

Prometrium – Micronized progesterone.

Microgest – Indian Manufactured Micronized progesterone.

4 Corners Pharmacy is also able to supply the following Products

Combination HRT

Kliogest and Kliovance / Activelle are combination hormone therapies that replace estrogen and progesterone, two natural female hormones that the body slowly stops producing around the time of menopause.

Nuvelle – A combination HRT.

Prempro is approved for women with an intact uterus for the treatment of moderate to severe hot flashes and night sweats associated with menopause, the treatment of vaginal dryness, and the prevention of postmenopausal osteoporosis.

Premphase is an estrogen and progesterone combination used to treat the symptoms of menopause. It may also be used to treat certain menstrual disorders, osteoporosis, or other conditions as determined by your doctor.

Climen is indicated in patients (with intact uteri) suffering from climacteric symptomatology.
Climen therapy may be used as an adjunct in preventing osteoporosis in postmenopausal women.

Other Products

Intrinsa – provides a measured daily dose of testosterone via a discreetly placed patch on your body.

Dixarit – is used for preventative management of migraine headaches and menopausal flushing.

Livial – is a first choice comprehensive treatment for the relief of climacteric symptoms and prevention of osteoporosis in postmenopausal women as Livial contains tibolone – a selective tissue estrogenic activity regulator (STEAR) – which regulates estrogenic activity in a tissue selective way.

Tibofem – is a generic form of Livial. Tibofem contains tibolone – a selective tissue estrogenic activity regulator (STEAR) – which regulates estrogenic activity in a tissue selective way.


Arimidex is indicated for the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer.

Anastrozole is a non-steroidal aromatase inhibitor that decreases the amount of estrogen the body makes and is used in the treatment of some types of breast cancer.

Fempro – Generic Femara
Fempro is in a class of medications known as nonsteroidal aromatase inhibitors. It decreases the amount of estrogen produced by the body.

Tamoxifen (trade name Nolvadex) is a drug in pill form, taken orally, that interferes with the activity of estrogen (a female hormone). Tamoxifen has been used to treat both advanced and early stage breast cancer.

Natural Therapies for Menopause

Two Natural Dietary Supplements for the treatment of menopausal symptoms

Promensil – is a dietary supplement developed especially for women over 45

Remifemin – is an extract of the rootstock of the herb Cimicifuga Racemosa (Black Cohosh) used by millions of women worldwide for effective relief from menopausal symptoms.

Medications for the treatment of Osteoporosis

Evista – (raloxifene hydrochloride, 60 mg) has been approved for the prevention of osteoporosis in postmenopausal women. Evista, the first in a class of new drugs called selective estrogen receptor modulators (SERMs) to be approved by the FDA for marketing for the prevention of osteoporosis.

Ralista – is a generic form of Evista. Ralista is raloxifene hydrochloride, 60 mg. Ralista is made by Cipla (India).

Fosamax – is a bisphosphonate used to prevent and treat osteoporosis that occurs after menopause.

Fosamax (once weekly) – is the first and only oral medication approved for the treatment and prevention of postmenopausal osteoporosis in a once-weekly dosing regimen.

Osteofos-10 – is a generic form of Fosamax 10 mg manufactured by Cipla.

Osteofos-70 – is a generic form of Fosamax 70 mg manufactured by Cipla.

Cipla Ltd is a generic drug maker in Bombay India, which broke the patent monopolies held by the larger North American based companies to provide critically needed AIDS drugs to charities like Medicins sans Frontieres (Doctors without Borders) and patients who cannot afford the expensive brand-name versions.
India’s 31-year-old patent rules recognize only manufacturing processes and not the products themselves.

Fertility Medications

Serophene – is the brand name for a drug called clomiphene citrate, which has been on the market for over 25 years. Initial research indicated that clomiphene seemed to induce menstrual periods in women who were not menstruating or ovulating. Further research and testing showed that clomiphene could help certain nonovulating women get pregnant by stimulating the ovaries to produce an egg.

Fertomid – is Clomiphene Citrate.
Fertomid is a Generic of Clomid or Serophene and is made by Cipla in India.
Clomiphene citrate (brand name Clomid, Serophene) is used to induce ovulation. It revolutionized the field of infertility in the late 1950s.

PCOS Medications

The ovaries are the organs that produce the eggs in the female reproductive system. Polycystic ovary syndrome (PCOS) is a syndrome in which the ovaries are enlarged and have several fluid-filled sacs or cysts. These cysts may look like a string of pearls or a pearl necklace. A woman can develop one cyst or many cysts. Polycystic ovaries are usually 1.5 to 3 times larger than normal. Women with PCOS may experience a number of other symptoms as well. PCOS is a leading cause of infertility and is the most common reproductive syndrome in women of childbearing age.

Diane 35
Birth control pills treat a few of the symptoms of PCOS. They usually bring on a period each month (though some women with PCOS do not have regular periods even while taking birth control pills) which is important for women who do not have regular cycles because lack of menstruation puts a woman at higher risk for endometrial cancer. Some women find that hair problems either lessen or stop getting worse while on the pill, particularly with Diane-35 or Dianette (which contains cyproterone acetate, an anti-androgen).

Ginette 35 – is a generic version of Diane 35 made by Cipla Pharmaceuticals in India.

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