Health QuestionsCategory: MedicationsDepakote and mixed states
sundae asked 3 years ago

 My doctor is thinking about putting me on Depakote for my anxiety-ridden mixed state.  Any stories here on Depakote and mixed states?

17 Answers
jupitergal answered 3 years ago

Re: Depakote and mixed states
I hate depakote. It evened out my mood, meaning most of the time I was pretty calm and didn’t feel much of anything.  But I stayed on the “low” end of the bipolar spectrum, not nearly as low as I can get on the lamictal.  BUT It made my hair fall out, made me an insomiac at night and fatigured during the day and made me ravenous, and the pounds piled on.  It also slows your metabolism and I’m still trying to lose the weight I gained on it and it means I have to work a lot harder than I did before I got on it.  SO it didn’t do much for my motivation. I think I was less anxious on it, I was basically apathetic  The weight gain and hair loss just started becoming a real problem for me and it was countering whatever mood stabilizing effects I might have been getting.  I wouldn’t go back on it for those reasons.  
I forgot, like rage said below…It also made me an insomiac.

mania answered 3 years ago

Re: Depakote and mixed states
Quote from Samsara on 28. Aug 2006 at 18:20:

The weight = dosage thing is a bit wacked if you ask me. I know a guy who is over 300 lbs and he takes less than I do. I think it has more to do with how quickly your body processess it.

For me it is working very well. A mixed state is an awful thing to go through. Hope things work out well for you.

You’re most likely right.
I’m glad to hear it’s working for you.  Success stories are always good.

ignatz answered 3 years ago

Re: Depakote and mixed states
I went into the hospital with a nasty mixed state– felt horrible.  I am BP 2– though no one figured that out until this particular episode.  (I also take Effexor, but obviously it wasn’t doing it at that point.) They put me on high-dose Depakote and I was fine within 3 days.  I say, try it, load it up quick, it might work well.

crazycatlady answered 3 years ago

Re: Depakote and mixed states
I just started taking Depakote this past saturday for migraines, or so my psych said. But since they can’t rule out bi polar, I reckon it will work for this too, huh? So far, I just feel kinda like a lump, I’m here, that’s about it. Oh and I can’t SLEEP…..agggghhhh

ragemaxis answered 3 years ago

Re: Depakote and mixed states
I ended up sleepless and psychotic on depakote.