Health QuestionsCategory: TreatmentsMixing Benzos?
scott asked 3 years ago

Hi,
 
I’m new to klonopin and had been switched over from ativan since this is longer acting.  Thing is, it doesn’t work as well for me with sleep.   When I was being weaned over I found a killer combo.  Taking 1 klonopin with 2mg ativan gave me the best 6-7 hours sleep of my life.  My p-doc says they are the same thing and to pick one or the other, you can’t have both.  I only use them at night as these does for sleep.  I don’t see the problem.  The other thing I noticed, when the klonopin wears off, about 12 hours later I get a pretty wicked rebound depression for about two hours.  Does this wear off or is it just part of the benzo cycle?  I noticed it with ativan too but it didn’t last nearly as long as the klonopin.
Also taking zoloft for depression and trileptal as a mood stabilizer at night.  I know eventually if I get enough trileptal, I won’t need as much, if any, of the benzo because trileptal is pretty sedating for me and I take it at night too.  Just looking for thoughts since 3-4 hours sleep don’t cut it with bipolar.  Gotta have at least six or I’m cycling all over the place.  Thanks!

4 Answers
gretl answered 3 years ago

Re: Mixing Benzos?

Used judiciously, this is not unheard of.  Yeah, they’re essentially “the same thing” but like you probably know, Ativan hits quicker … so might help you fall asleep … and Klonopin lasts longer … so might help you stay asleep.  But pdocs are often jumpy about benzos in general, and well gosh if a person has TWO at home, just imagine the abuse or resale potential.  *rolls eyes*
 
The rebound depression is a problem though, and it’s possible that the two are potentiating the side effect.  Keep an eye on it.  (Magnesium supplements are sometimes good for helping you sleep longer, and might help reduce the K doses.   ?)
 
I did find Trileptal worked well for a nighty-night med.

SnaiLuv answered 3 years ago

Re: Mixing Benzos?
Ditto completely on the Doc’s attitudes. *sigh*
I’ve taken the exact combo you’re talking about and yes, it’s the best sleep in the world. The Ativan hits quicker, and the Klonopin lasts, so you’re getting both needs met. I think I take like 1 mg Ativan and .5 Klonopin and that seems to be pretty money.  
Neither of them are precisely **my** prescriptions, but  I use them in a judicious and responsible manner that does not involve resale values. Smiley  
I’m also still in the throes of coming off a three-year dalliance with Lexapro, so I need something to help with the electric brain shocks and vertigo. Ativan’s been okay, benadryl helps, but i need to get my klonopin refillled.

jookeyman answered 3 years ago

Re: Mixing Benzos?
The depression from the Klonopin happens when it kicks in good. It isn’t really depression, it’s the action of the drug. Ativan and Klonopin are not the same. They are lumped together in the same family but they are quite different. Klonopin was developed for epilepsy.
 
Jook

mania answered 3 years ago

Re: Mixing Benzos?
Quote from gretl on 24. Apr 2006 at 06:27:

I did find Trileptal worked well for a nighty-night med.  

 
Holy Crap!  Just trying to get through brushing my teeth after upping my dose last night was a major event!
 
m

scott asked 3 years ago

Hi,
 
I’m new to klonopin and had been switched over from ativan since this is longer acting.  Thing is, it doesn’t work as well for me with sleep.   When I was being weaned over I found a killer combo.  Taking 1 klonopin with 2mg ativan gave me the best 6-7 hours sleep of my life.  My p-doc says they are the same thing and to pick one or the other, you can’t have both.  I only use them at night as these does for sleep.  I don’t see the problem.  The other thing I noticed, when the klonopin wears off, about 12 hours later I get a pretty wicked rebound depression for about two hours.  Does this wear off or is it just part of the benzo cycle?  I noticed it with ativan too but it didn’t last nearly as long as the klonopin.
Also taking zoloft for depression and trileptal as a mood stabilizer at night.  I know eventually if I get enough trileptal, I won’t need as much, if any, of the benzo because trileptal is pretty sedating for me and I take it at night too.  Just looking for thoughts since 3-4 hours sleep don’t cut it with bipolar.  Gotta have at least six or I’m cycling all over the place.  Thanks!

1 Answers
gretl answered 3 years ago

Re: Mixing Benzos?

Used judiciously, this is not unheard of.  Yeah, they’re essentially “the same thing” but like you probably know, Ativan hits quicker … so might help you fall asleep … and Klonopin lasts longer … so might help you stay asleep.  But pdocs are often jumpy about benzos in general, and well gosh if a person has TWO at home, just imagine the abuse or resale potential.  *rolls eyes*
 
The rebound depression is a problem though, and it’s possible that the two are potentiating the side effect.  Keep an eye on it.  (Magnesium supplements are sometimes good for helping you sleep longer, and might help reduce the K doses.   ?)
 
I did find Trileptal worked well for a nighty-night med.

SnaiLuv answered 3 years ago

Re: Mixing Benzos?
Ditto completely on the Doc’s attitudes. *sigh*
I’ve taken the exact combo you’re talking about and yes, it’s the best sleep in the world. The Ativan hits quicker, and the Klonopin lasts, so you’re getting both needs met. I think I take like 1 mg Ativan and .5 Klonopin and that seems to be pretty money.  
Neither of them are precisely **my** prescriptions, but  I use them in a judicious and responsible manner that does not involve resale values. Smiley  
I’m also still in the throes of coming off a three-year dalliance with Lexapro, so I need something to help with the electric brain shocks and vertigo. Ativan’s been okay, benadryl helps, but i need to get my klonopin refillled.

jookeyman answered 3 years ago

Re: Mixing Benzos?
The depression from the Klonopin happens when it kicks in good. It isn’t really depression, it’s the action of the drug. Ativan and Klonopin are not the same. They are lumped together in the same family but they are quite different. Klonopin was developed for epilepsy.
 
Jook

mania answered 3 years ago

Re: Mixing Benzos?
Quote from gretl on 24. Apr 2006 at 06:27:

I did find Trileptal worked well for a nighty-night med.  

 
Holy Crap!  Just trying to get through brushing my teeth after upping my dose last night was a major event!
 
m