Health QuestionsCategory: Treatmentsschizoaffective meds..the great hunt
lookabunny asked 3 years ago

I’m schizoaffective (bipolar type) and I’m still on the hunt.
 
Trileptal controls my mood and seizures most of the time, but the AP meds are a pain.
 
I cycled through most of the atypicals. They had little or no effect on the positive symptoms which is what I have the most trouble with.
 
Moban didn’t work either so now I’m on Trilafon. It helps a little and the side-effects are next to nothing. Cogentin helps a little though. Have to see the doc tomorow, maybe he can help me.
 
Oh yeah I’m also under a commitment order at the moment..been in a partial program for 3 months now and I have learned a lot..but it gets rather old. I just hope I can get on the right cocktail! I showed my first symptoms around the age of 7 so I’m damn well ready for SOMETHING to work.

8 Answers
Kassiane answered 3 years ago

Re: schizoaffective meds..the great hunt
Oh boy the med go round!
 
There’s Clozaril (but kiss seizure control goodbye, and expect to be a human pincushion. Otherwise it’s the best of the best).
 
I liked Thorazine personally, for serious mixed mania, until it gave me a half hour partial complex seizure. In spite of that, it’s a good PRN.
 
Stay away from Navane if you can, it causes the worst twitchy EPS *ever*. And DAMN was I a zombie (again, mixed mania, I’m BPI but it’s all a big continuum).
 
Sometimes mixing APs works, but unless you like having TD & reversable EPS you have to be realllly careful.  
 
That’s my experience, anyway. Good luck tomorrow.
 
Kassiane

lookabunny answered 3 years ago

Re: schizoaffective meds..the great hunt
Quote from Kassiane on 04. May 2006 at 17:10:

Oh boy the med go round!

There’s Clozaril (but kiss seizure control goodbye, and expect to be a human pincushion. Otherwise it’s the best of the best).

I liked Thorazine personally, for serious mixed mania, until it gave me a half hour partial complex seizure. In spite of that, it’s a good PRN.

Stay away from Navane if you can, it causes the worst twitchy EPS *ever*. And DAMN was I a zombie (again, mixed mania, I’m BPI but it’s all a big continuum).

Sometimes mixing APs works, but unless you like having TD & reversable EPS you have to be realllly careful.

That’s my experience, anyway. Good luck tomorrow.

Kassiane

 
Thanks, luck would be good right now. I haven’t had much of an issue with TD so far. The trilafon was causing it at first, but it just sort of stopped. I’ll take TD any day over the restless arms and legs I got from the Moban. I’m hoping they can tweak the trilafon a little bit since I am responding better to it than anything else I’ve tried. I’m think adding an atypical could help my loose/disorganized thoughts..it be nice to be able to read and actually comprehend!  
 
At least my mood’s been pretty stable. I stay in a hypomanic state most of the time which is relief considering how the full blown manic state gets me (and everyone else) into trouble.

martasi answered 3 years ago

Re: schizoaffective meds..the great hunt
Thanks for the medication feedback. I’ve been diagnosed as both BP-mixed states and schizoaffective (at different times). The big debate is whether these illnesses are just stopping points on a long contitnuum or whether they’re distinct illnesses.  
 
It’s very frustrating to have symptoms of both disorders and to find which meds work. I think body chemistry has something to do with it too.  I wish doctors knew more about brain biochemistry in determining which meds will be most effective. For me, Haldol is the most effective medication, yet it’s not typically prescribed for BP, which leads me to believe one of my big issues is with dopamine regulation – not a typical BP issue, more a schizophrenia/schizoaffective problem. But I have other symptoms that are definitely BP. I’d like to find a doctor who could decide definitely what I “have.”  
 
Thanks for starting this section.
 
martasi

lookabunny answered 3 years ago

Re: schizoaffective meds..the great hunt
I’m no doctor, but it sounds a lot like your schizoaffective. Reading the DSM might help explain things a little better, but nothing tops a good doc.

dcentity2000 answered 3 years ago

Re: schizoaffective meds..the great hunt
If you are biploar, atypicals may not be for you. Anecdotally, some patients have told me that the antidepressant effects of atypical antipsychotics, particularly Questiapine and Clozapine, played against them on the mania front.
 
They also complained that the stimulant effect of some of some drugs (such as Aripiprazole) played against them in the same way.
 
However, antupsychoics in general help to control mood swings, so we’re really just nit picking here. As far as I know, Ziprasidone is the best antipsychotic for bipolar patients (again, purely anecdotal).
 
Might I suggest a typical atipsychotic? The gold standard of all antipsychotics is Trifluoperazine, sometimes referred to a Stelazine (brand name). There’s also Haloperidol close behind, but it is used less nowadays as it is typically associated with unwanted movement. Both those drugs are especially good for panic and anxiety.
 
 
 
Rich::