Bleeding disorders are the opposite of thrombophilia, and include hemophilia, von Willebrand’s disease, and thrombocytopenia. Rather than causing a deep vein thrombosis or embolism, bleeding disorders make clot formation difficult. Continue reading “Von Willebrand’s is the Most Common Bleeding Disorder” »
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Hemostasis refers to the complicated chemical interplay that maintains blood viscosity, or thickness. Blood disorders occur when hemostasis falls out of balance. If blood becomes too thin, it loses the ability to form the blood clots that stop bleeding. Continue reading “Hemostasis and Blood Clotting Disorders” »
Hemophilia’s main symptom is bleeding. Defects in blood coagulation factors result in low levels of fibrin, which impairs the body’s ability to create strong blood clots. Continue reading “Hemophilia Causes Bruising and Mild to Severe Bleeding” »
In addition to bleeding, people with hemophilia must be on the watch for a number of health complications. Medications must be controlled carefully; taking aspirin, NSAIDs and other blood-thinning drugs can lead to serious consequences. Dental hygiene must be carefully maintained. Continue reading “Good Dental Hygiene, Avoiding Aspirin and Other NSAIDs” »
Hemophilia is a blood disorder that prevents blood from clotting properly, leading to uncontrolled bleeding. Hemophilia is actually a collection of several different genetic disorders passed on by heredity. The two most common types are hemophilia A and hemophilia B. Continue reading “The Hemophilias: Genetic Disorders Passed from Mother to Son” »
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After having my menstrual period, after 2-3 days, I got vaginal thrush and then I used the thrush cream. However, now I got orange colour discharge after using the thrush cream. I am worried about it. I am about 27 years old woman. What should I do? Is any treatment required for it or is it normal? Continue reading “Experiencing orange colour discharge while using vaginal thrush cream” »
I have been experiencing bleeding for last about 15 days. I am using copper-T. I am also having stomach pain and back pain. It feels as if something has been stuffed inside my stomach or as if something has been pinching inside. What is the reason for the pain? Continue reading “Stomach pain and back pain while being on copper-T” »
Joyful Joints – Put Out the Pain of Osteoarthritis! You may experience it during summer because of rain and humidity, or in wintertime due to the cold. Others may notice it when they exercise too hard or sit too long. The pain of osteoarthritis may interrupt your joy of watching seasonal colors change or getting a good workout. Continue reading “How is osteoarthritis different from rheumatoid arthritis?” »
European history beckons with blood disorder ‘Hemophilia’ for centuries together. Hailed as a ‘Royal Disease’, because Queen Victoria, who was the carrier of the gene, transmitted this disease to her sons and daughters who belonged to Royal families of Spain, Germany and Russia.
Hemophilia, a rare genetic blood disorder, affects mostly young boys and men. An estimated of over 50000 people across the globe are suffering from hemophilia disorder. In US alone, over 17000 males are born with this disease.
Hemophilia is a rare genetic blood disorder. It is hereditary in nature. This disorder prevents coagulation of blood. This leads to uncontrollable bleeding. In fact, it is worst in children, when bleeding fails due to absence of specific proteins called ‘factors’. These factors are necessary to prevent excessive clotting.
There are there two types of Hemophilia
Hemophilia A: This is caused due to lack of blood clotting of factor VIII. Approximately 85 percent of hemophiliacs suffer from this type.
Hemophilia B: This is caused due to deficiency of factor IX.
Hemophilia C: This caused due to deficiency of factor XI
Hemophilia is a rare hereditary disorder. It is mostly passed on from mother to the sons. The reason behind this rare transmission, it is caused by the mutation to a single recessive gene on the X chromosome.
Biologically, females have two X chromosomes, while males have one X and one Y chromosome. Which means, that females carry one of the hemophilia gene in one of her X chromosome. If she becomes pregnant, chances are her son will have the disease, while her daughter becomes a carrier of the gene.
So far, in about one-third of the children with hemophilia, there is no family history of the disorder. Normally, the disorder results due to creation of new gene mutation. This genetic defect affects due to the following questions:
- How much clotting factor a person will produce?
- How the factor will function?
Based on these questions, medical practitioners came to a conclusion that the less normal clotting factor you have, the more severity is the hemophilia.
Being a bleeding disorder, the most common symptom of hemophilia is the non-stop excessive bleeding and bruising. Defect in blood clotting factors results in low levels of fibrin. This impairs the body’s ability to create strong blood clots.
Bruises normally occur from minor accidents. This causes swelling, where a large number of blood clots are formed under the skin.
Hemophilia signs are often characterized by bleeding from the nose, mouth and gums. Daily brushing or any kind of dental procedures is a sure symptom.
Bleeding into a joint
This can lead to excruciating chronic arthritis, deformity and crippling with repeated occurrences.
Bleeding into the muscles
Bleeding into the muscles can cause swelling, pain, and redness. This can cause increased pressure on tissues and nerves, resulting in deformity.
Bleeding from injury or bleeding in the brain
Bleeding from injury, or spontaneously in the brain, is the most common cause of death in children with hemophilia. A brain hemorrhage can occur from even a small bump on the head. It could lead into blindness, retardation and a variety of neurological deficits.
WHOM TO CONSULT?
A child physician or a pathologist will definitely assist you with correct diagnosis and treatment for a healthy tomorrow.