Xanax (alprazolam). Xanax is the most potent and known as being the most addictive of all the benzos, so use with caution if there’s any chance you need to take this med daily or have the slightest hint of substance abuse. With all other benzos you can withdrawal using another benzo. Not Xanax. With Xanax you can discontinue only with Xanax, no other benzo will do. Xanax also has the worst side effect profile of the benzos, it could mess with your sleep, mess with your hormones, mess with your weight and just mess with you in general like a regular anticonvulsant and not side effect-free benzo. But none of the rare side effects, what few there are, is particularly freaky. The dosage depends on the ailment, and can range from 0.25 to 10mg a day, although 4-6mg a day is the usual effective dose for most people tolerate Xanax as a daily med for a panic/anxiety disorder. Given how potent Xanax is and how it actually has side effects, that 0.25mg to start and going from there seems like the best bet. Also comes in an XR formulation, similar, one presumes, to Tranxene’s once-a-day tablet. Unless it’s just some patent protection maneuver. We really don’t know. Xanax’s half-life is 11 hours. Pfizer.